COVID-19/SARS-CoV-2 resources & information
World Health Organization - WHO
Center for Disease Control - CDC
Springer Nature public access resource center
NIH Literature Hub
Lancet resource center
Local resources & suppliers:
NANOPEC offers filtration and bio-assay substrates, contact Mario Blanco
1. Nano-porous ceramics that can be used to test for viral RNA, with 50 nanometer pore size it will contain the virus and all other soluble proteins will pass through but not particles as large as NCOV-19. RNA is attracted to the surface of our ceramic and assays can be done in situ without transfer. The ceramic is transparent in the IR so FTIR can also be used in situ.
2. With an available capture antibody we can offer avidin modified surfaces to bind a biotinylated antibody. A secondary, cross-species antibody can then be used to detect fluorescence. We amplify it by 3,000% with our photo-active ceramic.
3. Culture cell media: we can grow cells, such as epithelial lung cells 30% faster on our cell culture device. These should be useful to test hypothesis for binding and HTS studies.
COVID-19 infection map from Johns Hopkins
Genomic epidemiology of CoV-19
Fierce Healthcare/Fierce Pharma Coronavirus virtual series, March 30-April 1 (free webinar)
Reference on environmental persistence:
Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. Kampf, G. et al. Journal of Hospital Infection, Volume 104, Issue 3, 246 - 251
currently, the emergence of a novel human coronavirus, SARS-CoV-2, has become a global health concern causing severe respiratory tract infections in humans. Human-to-human transmissions have been described with incubation times between 2-10 days, facilitating its spread via droplets, contaminated hands or surfaces. We therefore reviewed the literature on all available information about the persistence of human and veterinary coronaviruses on inanimate surfaces as well as inactivation strategies with biocidal agents used for chemical disinfection, e.g. in healthcare facilities. The analysis of 22 studies reveals that human coronaviruses such as Severe Acute Respiratory Syndrome (SARS) coronavirus, Middle East Respiratory Syndrome (MERS) coronavirus or endemic human coronaviruses (HCoV) can persist on inanimate surfaces like metal, glass or plastic for up to 9 days, but can be efficiently inactivated by surface disinfection procedures with 62–71% ethanol, 0.5% hydrogen peroxide or 0.1% sodium hypochlorite within 1 minute. Other biocidal agents such as 0.05–0.2% benzalkonium chloride or 0.02% chlorhexidine digluconate are less effective. As no specific therapies are available for SARS-CoV-2, early containment and prevention of further spread will be crucial to stop the ongoing outbreak and to control this novel infectious thread.